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- LilLil
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- LyyLzy
- Lewis, Jerry Lee with Page, Jimmy
- Lewis, Jerry Lee with Robertson, Robbie
- Lewis, Jerry Lee with Springsteen, Bruce
- Lewis, Jerry Lee with Stewart, Rod
- Lewis, Jerry Lee with Young, Neil
- Lewis, Jimmy (Soul/Blues singer/songwriter/producer)
- Lewis, Jodee
- Lewis, Joe (US techno/acid house producer)
- Lewis, John (pianist, member of Modern Jazz Quartet)
- Lewis, Jon Peter
- Lewis, Juliette (actress)
- Lewis, Ksenia
- Lewis, Laurie (bluegrass artist and violinist)
- Lewis, Laurie & Right Hands, The
- Lewis, Laurie and Rozum, Tom
- Lewis, Leon
- Lewis, Leona
- Lewis, Leona / Avicii
- Lewis, Leona feat. Allen, Robert
- Lewis, Leona feat. Childish Gambino
- Lewis, Leona feat. K2 Family
- Lewis, Leona feat. Loot
- Lewis, Leona featuring Ne‐Yo
- Lewis, Lesle
- Lewis, Lilli
- Lewis, Linda
- Lewis, Linda Gail
- Lewis, LunchMoney
- Lewis, Marcia
- Lewis, Margaret
- Lewis, Meade Lux
- Lewis, Mel (American jazz drummer)
- Lewis, Michelle (singer-songwriter)
- Lewis, Michelle (Attended Berklee College of Music)
- Lewis, Molly (Australian alternative artist)
- Lewis, Monica
- Lewis, Olivia
- Lewis, Parker
- Lewis, Phil (heavy metal vocalist)
- Lewis, Quinn
- Lewis, Ramsey
- Lewis, Ramsey & Wilson, Nancy
- Lewis, Ramsey, Trio, The
- Lewis, Rhys
- Lewis, Sam (UK based singer, songwriter and guitarist)
- Lewis, Shari
- Lewis, Shaznay
- Lewis, Simon (Australia ambient/world musician)
- Lewis, Smiley
- Lewis, Sylvie
- Lewis, Ted
- Lewis, Ted and His Band
- Lewis, Tom (singer and songwriter of nautical songs, sea shanties)
- Lewis, Tom E.
- Lewis, Trey
- LEWIS, TYLER (British pop singer)
- Lewis, Webster
- Lewis, Willie and His Negro Band
- Lewo
- Lewsberg (Dutch rock band)
- Lex (Greek rapper)
- LEX (Japanese Hip-Hop Artist)
- LEX (Rap GR)
- Lex (US furry electronic music / visual artist, Lextunes)
- Lex (Greek electronic music producer and DJ)
- LEX (japanese artist.)
- Lex & Klatten
- Lex Amor
- Lex Leosis (female rapper)
- Lex Luthorz (Spanish hip hop producer)
- Lex Talion
- LEX the Lexicon Artist (Oakland rapper)
- Lexa (Brazilian singer)
- Lexa & Hyperanhas
- Lexa & MC Lan
- Lexa feat. Groove, Gloria
- Lexa ft. Groove, Gloria
- Lexa, Anthony
- Lexer (DJ/producer)
- Lexer & Pusch, Nico
- Lexer feat. Fran
- Lexer feat. Humble, Belle
- Lexer feat. IDER
- Lexer feat. Janssens, Audrey
- Lexer, Alexandra
- Lexi (gospel artist)
- Lexi Jayde
- Lexia (Alexia Rodriguez)
- Lexica
- Lexicon (German trance/techno duo Levent Faki & Jost Gerischer)